GPR83

Across TCGA patient cohorts, GPR83 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,191 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR83-associated proteins across cancer lineages are RRBP1, AP4E1, and UPP1. Each is linked with GPR83 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR83-to-partner and partner-to-GPR83 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR83 versus RRBP1 in LSCC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR83→partner) and Y-score (partner→GPR83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RRBP1 →	-0.370	-0.298	<.001	<.001	3	4
CCRCC	AP4E1 →	-0.274	-0.167	<.001	.001	3	4
GBM	UPP1 →	-0.627	-0.584	<.001	<.001	3	4
LSCC	PAXBP1 →	+0.189	+0.223	<.001	<.001	3	3
GBM	ACTBL2 →	-0.281	-0.650	<.001	.001	3	3
GBM	ACTR2 →	-0.172	-0.751	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,191 associations by consensus.

GPR83 vs RRBP1 — LSCC

Explore this scatter interactively →