GPR150

Across TCGA patient cohorts, GPR150 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR150-associated genes across cancer lineages are IGKV2OR2-2, SEC22B2P, and RNA5SP411. Each is linked with GPR150 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR150-to-partner and partner-to-GPR150 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGKV2OR2-2 grouped by GPR150-low versus GPR150-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR150→partner) and Y-score (partner→GPR150) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-2 →	+0.218	+4.344	.001	.002	3	1
UCEC	SEC22B2P →	+0.126	+4.474	<.001	.002	3	1
UCEC	RNA5SP411 →	+2.425	+4.393	<.001	.002	3	1
UCEC	MIR4710 →	+0.797	+4.616	<.001	.001	3	1
UCEC	MIR3136 →	+0.779	+4.184	.008	.004	3	1
UCEC	MIR3657 →	+0.564	+4.496	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

IGKV2OR2-2 by GPR150 expression — UCEC

Explore this box plot interactively →