Q-omics provides the consensus-scored MIR3657 profile across patient tissues and cancer cell-line models. MIR3657 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR3657 is differentially expressed in 4, with the highest sampling consensus in KIRC. Additionally, MIR3657 RNA expression shows 14,471 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight UVM, KIRC, and DLBC as cancer lineages where MIR3657 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR3657 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR3657 survival associations across molecular data types. MIR3657 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR3657 RNA expression–survival associations across cancer types. High MIR3657 expression shows unfavorable associations in UVM, PAAD, CHOL, UCEC and KIRC, but favorable associations in BLCA. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR3657 RNA expression.
This table summarizes MIR3657 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR3657. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR3657 shows higher tumor expression in KIRC, LIHC, LUSC and HNSC. The KIRC box plot shows higher MIR3657 RNA expression in tumor versus normal tissue (log2 FC = +0.237, t-test p = .004).
This table shows molecular features associated with MIR3657 in patient tissues and cancer cell lines. In patient samples, MIR3657 shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
