GPR148

Across TCGA patient cohorts, GPR148 mutation is significantly associated with the RNA expression of many other genes, with 534 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GPR148-associated genes across cancer lineages are MIR760, NDUFA4P2, and RNU6-503P. Each is linked with GPR148 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR148-to-partner and partner-to-GPR148 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR760 grouped by GPR148-low versus GPR148-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR148→partner) and Y-score (partner→GPR148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR760 →	+0.513	+2.182	<.001	.007	3	3
LUAD	NDUFA4P2 →	+0.238	+2.914	<.001	.006	3	2
LUAD	RNU6-503P →	+0.425	+3.722	<.001	<.001	3	2
UCEC	RNA5SP461 →	+0.278	+4.601	<.001	.003	3	2
SKCM	KRT18P7 →	+0.141	+2.846	.001	.002	3	2
SKCM	RN7SL377P →	+0.188	+2.109	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 534 associations by consensus.

MIR760 by GPR148 expression — UCEC

Explore this box plot interactively →