GPR148

Across TCGA pan-cancer cohorts, GPR148 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GPR148’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GPR148 RNA is repressed in tumor relative to normal tissue. In most cancer types GPR148 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and STAD are the cancer types where GPR148 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPR148 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.006	.025	3	view →
KIRC	All	II,III,IV	−0.014	.013	2	view →
STAD	All	III,IV	−0.103	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GPR148–THCA

Open the THCA breakdown →