GPR148

Across TCGA cell cohorts, GPR148 RNA expression is significantly associated with the go_rna of many other GO terms, with 253 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GPR148-associated GO terms across cancer lineages are DNA synthesis involved in DNA repair, Regulation of arachidonate secretion, and Positive regulation of sodium ion transport. Each is linked with GPR148 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR148-to-partner and partner-to-GPR148 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA synthesis involved in DNA repair grouped by GPR148-low versus GPR148-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR148→partner) and Y-score (partner→GPR148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DNA synthesis involved in DNA repair →	+0.051	+0.009	.004	.002	3	2
LUNG_NSCLC_LUAD	Regulation of arachidonate secretion →	+0.169	+0.010	.004	.007	3	2
LUNG_NSCLC_LUAD	Positive regulation of sodium ion transport →	-0.157	-0.008	.001	.002	3	2
LUNG_NSCLC_LUAD	Regulation of sodium ion transmembrane transport →	-0.076	-0.007	.003	.008	3	2
LUNG_NSCLC_LUAD	Intracellular potassium ion homeostasis →	-0.141	-0.014	.001	.008	3	2
LUNG_NSCLC_LUAD	Depyrimidination →	+0.089	+0.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

DNA synthesis involved in DNA repair by GPR148 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →