GOLGA8T

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA8T mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA8T-associated genes across cancer lineages are MIR133B, MIR1258, and FAM243A. Each is linked with GOLGA8T in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8T-to-partner and partner-to-GOLGA8T results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR133B grouped by GOLGA8T-low versus GOLGA8T-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8T→partner) and Y-score (partner→GOLGA8T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR133B →+0.356+8.066<.001.00731
UCECMIR1258 →+0.509+8.066<.001.00731
UCECFAM243A →+0.069+8.066<.001.00731
UCECRNU7-95P →+0.562+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MIR133B by GOLGA8T expression — UCEC

Box plot of MIR133B in GOLGA8T-low vs GOLGA8T-high samples in UCEC.

Explore this box plot interactively →

Exploration