GOLGA8T

Across TCGA pan-cancer cohorts, GOLGA8T RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of GOLGA8T’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GOLGA8T RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA8T is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and KICH are the cancer types where GOLGA8T tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA8T RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.272	<.001	7	view →
BRCA	All	III,IV	−0.095	<.001	6	view →
KICH	All	II,III,IV	+0.096	.004	5	view →
HNSC	Female	III,IV	+0.034	.041	2	view →
ESCA	Female	All	−0.090	.041	1	view →
KIRC	Male	IV	+0.048	.030	1	view →
LUSC	Male	II,III,IV	−0.043	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

GOLGA8T–THCA

Open the THCA breakdown →