GOLGA8F

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA8F mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA8F-associated genes across cancer lineages are ATF4P2, TMEM271, and MIR6129. Each is linked with GOLGA8F in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8F-to-partner and partner-to-GOLGA8F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATF4P2 grouped by GOLGA8F-low versus GOLGA8F-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8F→partner) and Y-score (partner→GOLGA8F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECATF4P2 →+0.050+3.599<.001.00731
UCECTMEM271 →+0.826+4.677<.001<.00131
UCECMIR6129 →+1.134+4.818<.001<.00131
UCECRN7SL134P →+0.237+3.599<.001.00731
UCECMIR1915 →+0.528+4.133<.001.00231
UCECRPS29P31 →+0.429+4.715.003<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

ATF4P2 by GOLGA8F expression — UCEC

Box plot of ATF4P2 in GOLGA8F-low vs GOLGA8F-high samples in UCEC.

Explore this box plot interactively →

Exploration