golgin A7 family member BGenealiases: C10orf132 · C10orf133 · bA451M19.3 · bA459F3.4
Q-omics provides the consensus-scored GOLGA7B profile across patient tissues and cancer cell-line models. GOLGA7B expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, GOLGA7B is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, GOLGA7B RNA expression shows 16,932 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, HNSC, and UVM as cancer lineages where GOLGA7B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GOLGA7B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GOLGA7B survival associations across molecular data types. GOLGA7B RNA expression shows survival associations in the most cancer types (23), followed by mutation status (2) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GOLGA7B RNA expression–survival associations across cancer types. High GOLGA7B expression shows unfavorable associations in KIRC, ACC, SKCM, LIHC and KIRP, but favorable associations in LUAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify KIRC as the clearest survival context for GOLGA7B RNA expression.
This table summarizes GOLGA7B tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for GOLGA7B. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GOLGA7B shows higher tumor expression in HNSC, COAD, THCA, LUAD, KIRC and KIRP. The HNSC box plot shows higher GOLGA7B RNA expression in tumor versus normal tissue (log2 FC = +2.350, t-test p < 0.001).
This table shows molecular features associated with GOLGA7B in patient tissues and cancer cell lines. In patient samples, GOLGA7B shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, GOLGA7B RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BONE, while CRISPR and shRNA rows add functional-dependency signals in OESOPHAGUS and SKIN.
