GOLGA7B

Across TCGA pan-cancer cohorts, GOLGA7B RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of GOLGA7B’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where GOLGA7B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GOLGA7B is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, COAD, and THCA are the cancer types where GOLGA7B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA7B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+2.350	<.001	12	view →
COAD	All	IV	+2.184	<.001	12	view →
THCA	Male	III,IV	+2.024	<.001	11	view →
LUAD	All	III,IV	+1.892	<.001	11	view →
KIRC	Male	III,IV	+1.103	<.001	11	view →
KIRP	Female	All	+1.000	<.001	9	view →
STAD	All	II,III,IV	+0.606	.017	5	view →
LIHC	Male	II,III,IV	+1.255	.002	4	view →
BRCA	Female	II,III,IV	−0.583	<.001	4	view →
CHOL	All	All	+3.366	<.001	3	view →
LUSC	Male	All	+0.908	<.001	3	view →
READ	All	All	+1.787	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

GOLGA7B–HNSC

Open the HNSC breakdown →