GOLGA7B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA7B mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA7B-associated genes across cancer lineages are RNA5SP414, RNA5SP411, and UQCRFS1P2. Each is linked with GOLGA7B in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA7B-to-partner and partner-to-GOLGA7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by GOLGA7B-low versus GOLGA7B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA7B→partner) and Y-score (partner→GOLGA7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP414 →+1.465+3.840<.001.00731
UCECRNA5SP411 →+2.740+4.393<.001.00231
COADUQCRFS1P2 →+0.110+5.357.003.00631
COADTAB2-AS1 →+0.144+5.602<.001.00431
COADRN7SL386P →+0.247+5.357.003.00631
COADRN7SL186P →+0.245+5.790<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

RNA5SP414 by GOLGA7B expression — UCEC

Box plot of RNA5SP414 in GOLGA7B-low vs GOLGA7B-high samples in UCEC.

Explore this box plot interactively →

Exploration