GNAS-AS1

Across TCGA patient cohorts, GNAS-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,519 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAS-AS1-associated proteins across cancer lineages are SUPT6H, CMTR1, and ZFP64. Each is linked with GNAS-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GNAS-AS1-to-partner and partner-to-GNAS-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAS-AS1 versus SUPT6H in GBM, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAS-AS1→partner) and Y-score (partner→GNAS-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUPT6H →	+0.211	+0.567	<.001	<.001	3	4
GBM	CMTR1 →	+0.293	+0.574	<.001	<.001	3	4
GBM	ZFP64 →	+0.320	+0.440	<.001	<.001	3	3
GBM	ZFR →	+0.225	+0.484	<.001	<.001	3	3
UCEC	RERE_S642 →	+0.391	+0.542	.005	.006	3	3
UCEC	SH3BP4 →	-0.345	-0.611	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,519 associations by consensus.

GNAS-AS1 vs SUPT6H — GBM

Explore this scatter interactively →