GMNN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GMNN RNA expression is significantly associated with the protein abundance of many other proteins, with 18,692 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GMNN-associated proteins across cancer lineages are SMC2, SMC4, and NCAPG. Each is linked with GMNN in more than 8 cancer types. Because this analysis shows association rather than direction, both GMNN-to-partner and partner-to-GMNN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMNN versus SMC2 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMNN→partner) and Y-score (partner→GMNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSMC2 →+0.626+0.538<.001<.00139
GBMSMC4 →+0.619+0.584.001.00239
BRCANCAPG →+0.630+0.838<.001<.00139
OVCDC20_T70 →+1.137+0.818<.001.00239
BRCAMCM2_S41 →+0.763+0.631<.001<.00139
LUADRFC1_T506 →+1.072+0.729<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,692 associations by consensus.

GMNN vs SMC2 — GBM

Per-sample scatter of GMNN vs SMC2 in GBM (Pearson r = 0.42).

Explore this scatter interactively →

Exploration