GMDS-DT

Across TCGA patient cohorts, GMDS-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 15,904 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GMDS-DT-associated proteins across cancer lineages are ALDH6A1, DDAH2, and P3H2. Each is linked with GMDS-DT in more than 6 cancer types. Because this analysis shows association rather than direction, both GMDS-DT-to-partner and partner-to-GMDS-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMDS-DT versus ALDH6A1 in UCEC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMDS-DT→partner) and Y-score (partner→GMDS-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALDH6A1 →	+0.488	+0.409	.001	.002	3	7
COAD	DDAH2 →	+0.376	+0.207	<.001	<.001	3	6
HNSC	P3H2 →	-1.109	-0.589	<.001	<.001	3	5
BRCA	TSTD1 →	+0.526	+0.359	<.001	<.001	3	5
HNSC	VEZF1 →	+0.358	+0.746	<.001	<.001	3	5
BRCA	RPL7 →	-0.373	-0.317	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,904 associations by consensus.

GMDS-DT vs ALDH6A1 — UCEC

Explore this scatter interactively →