GK-IT1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GK-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,117 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GK-IT1-associated proteins across cancer lineages are ITGAM, MNDA, and BPI. Each is linked with GK-IT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GK-IT1-to-partner and partner-to-GK-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GK-IT1 versus ITGAM in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GK-IT1→partner) and Y-score (partner→GK-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMITGAM →+0.878+0.961<.001<.00138
GBMMNDA →+1.147+0.943<.001<.00138
GBMBPI →+1.269+0.949<.001<.00138
PDACELANE →+1.225+0.648<.001<.00138
PDACC5AR1_S327 →+0.967+0.474<.001<.00137
PDACCAMP →+1.397+0.621<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,117 associations by consensus.

GK-IT1 vs ITGAM — GBM

Per-sample scatter of GK-IT1 vs ITGAM in GBM (Pearson r = 0.74).

Explore this scatter interactively →

Exploration