GK-IT1

Across TCGA patient cohorts, GK-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,804 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible GK-IT1-associated GO terms across cancer lineages are Neutrophil migration, Response to type II interferon, and Response to tumor necrosis factor. Each is linked with GK-IT1 in more than 21 cancer types. Because this analysis shows association rather than direction, both GK-IT1-to-partner and partner-to-GK-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophil migration grouped by GK-IT1-low versus GK-IT1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GK-IT1→partner) and Y-score (partner→GK-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Neutrophil migration →	+0.044	+0.476	<.001	<.001	3	22
ESCA	Response to type II interferon →	+0.053	+0.830	<.001	<.001	3	21
ESCA	Response to tumor necrosis factor →	+0.038	+0.511	<.001	<.001	3	21
LAML	Granulocyte chemotaxis →	+0.048	+0.675	.002	<.001	2	22
ESCA	Positive regulation of inflammatory response →	+0.036	+0.612	<.001	<.001	3	21
ESCA	Response to interleukin-1 →	+0.034	+0.477	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,804 associations by consensus.

Neutrophil migration by GK-IT1 expression — ESCA

Explore this box plot interactively →