GHR

Across TCGA patient cohorts, GHR protein abundance is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GHR-associated genes across cancer lineages are HTATSF1, ARMC1, and MAN2B1. Each is linked with GHR in more than 1 cancer types. Because this analysis shows association rather than direction, both GHR-to-partner and partner-to-GHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHR versus HTATSF1 in LSCC, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GHR→partner) and Y-score (partner→GHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HTATSF1 →	-0.960	-0.535	.004	.001	1	1
LSCC	ARMC1 →	-0.554	-0.535	.002	.001	1	1
LSCC	MAN2B1 →	+0.509	+0.535	.007	.001	1	1
LSCC	CNPPD1 →	-0.665	-0.535	.006	.001	1	1
LSCC	RWDD3 →	-0.440	-0.535	.009	.001	1	1
LSCC	CDK2 →	-1.314	-0.535	.001	.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

GHR vs HTATSF1 — LSCC

Explore this scatter interactively →