GGT8P

Across TCGA patient cohorts, GGT8P mutation is significantly associated with the RNA expression of many other genes, with 129 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible GGT8P-associated genes across cancer lineages are RN7SKP216, RN7SKP132, and RNA5SP377. Each is linked with GGT8P in more than 1 cancer types. Because this analysis shows association rather than direction, both GGT8P-to-partner and partner-to-GGT8P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP216 grouped by GGT8P-low versus GGT8P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT8P→partner) and Y-score (partner→GGT8P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP216 →	+0.223	+4.621	.006	.008	3	2
UCEC	RN7SKP132 →	+0.302	+5.877	<.001	.001	3	2
LUSC	RNA5SP377 →	+0.544	+5.517	<.001	.001	3	2
LUSC	ZNF722P →	+0.998	+4.727	<.001	.001	3	2
LUSC	RN7SL101P →	+0.119	+4.297	.001	.009	3	2
GBM	MIR4537 →	+0.743	+5.352	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

RN7SKP216 by GGT8P expression — UCEC

Explore this box plot interactively →