Q-omics provides the consensus-scored MIR4537 profile across patient tissues and cancer cell-line models. MIR4537 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, MIR4537 is differentially expressed in 5, with the highest sampling consensus in COAD. Additionally, MIR4537 RNA expression shows 13,830 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight SKCM, COAD, and LSCC as cancer lineages where MIR4537 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4537 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4537 survival associations across molecular data types. MIR4537 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4537 RNA expression–survival associations across cancer types. High MIR4537 expression shows unfavorable associations in UVM and LGG, but favorable associations in SKCM, OV, HNSC and LUAD. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for MIR4537 RNA expression.
This table summarizes MIR4537 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4537. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4537 shows lower tumor expression in COAD and THCA and higher tumor expression in HNSC, LUAD and KIRC. The COAD box plot shows higher MIR4537 RNA expression in normal versus tumor tissue (log2 FC = −1.186, t-test p < 0.001).
This table shows molecular features associated with MIR4537 in patient tissues and cancer cell lines. In patient samples, MIR4537 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
