Q-omics provides the consensus-scored GGT8P profile across patient tissues and cancer cell-line models. GGT8P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, GGT8P is differentially expressed in 9, with the highest sampling consensus in KIRC. Additionally, GGT8P RNA expression shows 12,966 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, and TGCT as cancer lineages where GGT8P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GGT8P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GGT8P survival associations across molecular data types. GGT8P RNA expression shows survival associations in the most cancer types (23), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GGT8P RNA expression–survival associations across cancer types. High GGT8P expression shows unfavorable associations in LIHC, BRCA, DLBC, THYM and UVM, but favorable associations in KIRC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for GGT8P RNA expression.
This table summarizes GGT8P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for GGT8P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GGT8P shows lower tumor expression in COAD, KICH and BRCA and higher tumor expression in KIRC, LUAD and KIRP. The KIRC box plot shows higher GGT8P RNA expression in tumor versus normal tissue (log2 FC = +1.653, t-test p < 0.001).
This table shows molecular features associated with GGT8P in patient tissues and cancer cell lines. In patient samples, GGT8P shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
