GDF10

Across TCGA patient cohorts, GDF10 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,861 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GDF10-associated proteins across cancer lineages are SYNPO2, PLAC9, and RGN. Each is linked with GDF10 in more than 7 cancer types. Because this analysis shows association rather than direction, both GDF10-to-partner and partner-to-GDF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDF10 versus SYNPO2 in HNSC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF10→partner) and Y-score (partner→GDF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SYNPO2 →	+0.742	+0.625	<.001	<.001	3	7
UCEC	PLAC9 →	+1.168	+0.475	<.001	<.001	3	7
LUAD	RGN →	+0.553	+0.739	<.001	<.001	3	6
HNSC	SBSPON →	+0.952	+1.055	<.001	<.001	3	6
HNSC	DTNA_S458 →	+1.121	+0.542	<.001	<.001	3	6
LSCC	AKAP12_S612 →	+0.827	+0.524	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,861 associations by consensus.

GDF10 vs SYNPO2 — HNSC

Explore this scatter interactively →