GAL3ST3

Across TCGA cell cohorts, GAL3ST3 mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GAL3ST3-associated genes across cancer lineages are ACTRT1, GPR152, and F11. Each is linked with GAL3ST3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAL3ST3-to-partner and partner-to-GAL3ST3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTRT1 grouped by GAL3ST3-low versus GAL3ST3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAL3ST3→partner) and Y-score (partner→GAL3ST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ACTRT1 →	+0.014	+3.879	<.001	<.001	3	2
BLOOD_Leukemia	GPR152 →	+0.398	+3.534	<.001	.002	3	2
BLOOD_Leukemia	F11 →	+0.089	+3.662	<.001	<.001	3	2
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	FSHR →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	CCDC195 →	+0.043	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

ACTRT1 by GAL3ST3 expression — BLOOD_Leukemia

Explore this box plot interactively →