FZR1

Across TCGA patient cohorts, FZR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,046 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FZR1-associated proteins across cancer lineages are THOP1, HDGFL2, and CHAF1A. Each is linked with FZR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FZR1-to-partner and partner-to-FZR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZR1 versus THOP1 in OV, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZR1→partner) and Y-score (partner→FZR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THOP1 →	+0.286	+0.559	<.001	<.001	3	5
GBM	HDGFL2 →	+0.324	+0.340	<.001	<.001	3	5
OV	CHAF1A →	+0.620	+0.754	.002	<.001	2	5
LSCC	PRPF38A →	+0.251	+0.616	<.001	<.001	3	4
LSCC	PRPF39 →	+0.242	+0.555	<.001	<.001	3	4
GBM	BRD4 →	+0.324	+0.440	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,046 associations by consensus.

FZR1 vs THOP1 — OV

Explore this scatter interactively →