FOXRED2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXRED2 mutation is significantly associated with the RNA expression of many other genes, with 1,903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXRED2-associated genes across cancer lineages are RNU1-88P, RN7SL326P, and RNU6-4P. Each is linked with FOXRED2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXRED2-to-partner and partner-to-FOXRED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-88P grouped by FOXRED2-low versus FOXRED2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXRED2→partner) and Y-score (partner→FOXRED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU1-88P →+0.356+3.236.006.00533
CESCRN7SL326P →+0.094+3.345.001.00833
SKCMRNU6-4P →+0.387+2.587<.001<.00133
UCECCDCA2 →+0.786+4.021<.001<.00133
UCECRN7SL447P →+0.194+2.171<.001<.00133
BLCASS18L2P1 →+0.108+3.973.005.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,903 associations by consensus.

RNU1-88P by FOXRED2 expression — CESC

Box plot of RNU1-88P in FOXRED2-low vs FOXRED2-high samples in CESC.

Explore this box plot interactively →

Exploration