FNBP1L

Across TCGA cell cohorts, FNBP1L mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FNBP1L-associated genes across cancer lineages are GHRHR, OR1N2, and OOSP4B. Each is linked with FNBP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both FNBP1L-to-partner and partner-to-FNBP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by FNBP1L-low versus FNBP1L-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNBP1L→partner) and Y-score (partner→FNBP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GHRHR →	+0.069	+5.087	<.001	.004	3	1
LUNG_SCLC	OR1N2 →	+0.025	+5.029	<.001	.006	3	1
LUNG_SCLC	OOSP4B →	+0.233	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	KRTAP9-1 →	+0.040	+5.247	<.001	.001	3	1
LARGE_INTESTINE	CST8 →	+0.021	+4.415	<.001	.007	3	1
LARGE_INTESTINE	AWAT2 →	+0.017	+4.095	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GHRHR by FNBP1L expression — URINARY_TRACT

Explore this box plot interactively →