FNBP1L

Across TCGA pan-cancer cohorts, FNBP1L RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated FNBP1L data layer compared with 6 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FNBP1L RNA is associated with better overall survival. In most high-consensus cancer types, elevated FNBP1L expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.

KIRC, LGG, and MESO are the cancer types where FNBP1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.749	0.523	<.001	147	view →
LGG	OS	Median	All	0.361	0.532	<.001	54	view →
MESO	OS	Quartile	III,IV	0.391	0.734	.005	41	view →
CESC	DFS	Median	All	0.771	0.870	.001	38	view →
LIHC	DFS	Tertile	All	0.403	0.597	<.001	37	view →
BLCA	DFS	Tertile	All	0.220	0.517	.004	30	view →
COAD	OS	Median	II,III,IV	0.848	0.716	.004	29	view →
SARC	OS	Median	All	0.402	0.623	<.001	28	view →
LUSC	DFS	Quartile	III,IV	0.191	0.519	.009	26	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	19	view →
READ	OS	Tertile	III,IV	0.813	0.287	.008	18	view →
LAML	DFS	Median	All	0.511	0.249	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

FNBP1L–KIRC (OS)

Open the KIRC breakdown →