FNBP1L

Across TCGA pan-cancer cohorts, FNBP1L RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of FNBP1L’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where FNBP1L RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FNBP1L is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

BLCA, LIHC, and KICH are the cancer types where FNBP1L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FNBP1L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+1.155	<.001	10	view →
LIHC	All	II,III,IV	+1.198	<.001	9	view →
KICH	All	II,III,IV	−1.088	<.001	8	view →
KIRC	Male	II,III,IV	−0.531	.001	7	view →
UCEC	All	All	+0.815	<.001	6	view →
THCA	All	II,III,IV	−0.452	.006	6	view →
BRCA	All	II,III,IV	+0.418	<.001	6	view →
STAD	All	II,III,IV	+1.039	<.001	4	view →
LUAD	Male	All	+0.661	<.001	4	view →
CHOL	Female	All	+2.853	<.001	3	view →
LUSC	All	All	−0.377	.014	3	view →
PRAD	All	All	+0.551	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

FNBP1L–BLCA

Open the BLCA breakdown →