FKBP10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FKBP10 mutation is significantly associated with the RNA expression of many other genes, with 3,520 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP10-associated genes across cancer lineages are RNU6-511P, RN7SL362P, and MIR6500. Each is linked with FKBP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP10-to-partner and partner-to-FKBP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-511P grouped by FKBP10-low versus FKBP10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP10→partner) and Y-score (partner→FKBP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-511P →+0.662+4.163<.001.00132
LUSCRN7SL362P →+0.161+4.984.007.00932
LUSCMIR6500 →+1.267+5.273<.001.00632
LUADOR51A5P →+0.122+5.523<.001.00132
LUADDUX4L31 →+0.033+4.399<.001.00832
UCECRNA5SP405 →+0.158+3.058.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,520 associations by consensus.

RNU6-511P by FKBP10 expression — CESC

Box plot of RNU6-511P in FKBP10-low vs FKBP10-high samples in CESC.

Explore this box plot interactively →

Exploration