FGFBP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGFBP2 mutation is significantly associated with the RNA expression of many other genes, with 131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGFBP2-associated genes across cancer lineages are LINC02778, LINC-ROR, and UFD1. Each is linked with FGFBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFBP2-to-partner and partner-to-FGFBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02778 grouped by FGFBP2-low versus FGFBP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP2→partner) and Y-score (partner→FGFBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC02778 →+0.400+6.199<.001.00132
UCECLINC-ROR →+0.181+2.758<.001.00332
UCECUFD1 →+0.473+3.223.003.00931
UCECNANS →+0.739+3.202.001.00931
SKCMIFNA2 →+0.061+5.970<.001.00231
SKCMRNY4P14 →+0.552+5.362<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 131 associations by consensus.

LINC02778 by FGFBP2 expression — SKCM

Box plot of LINC02778 in FGFBP2-low vs FGFBP2-high samples in SKCM.

Explore this box plot interactively →

Exploration