FGFBP2

Across TCGA pan-cancer cohorts, FGFBP2 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated FGFBP2 data layer compared with 1 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FGFBP2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FGFBP2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LIHC show a favorable association.

KIRC, LIHC, and LGG are the cancer types where FGFBP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.741	0.557	<.001	107	view →
LIHC	DFS	Median	All	0.616	0.466	<.001	43	view →
LGG	OS	Tertile	All	0.424	0.612	<.001	41	view →
PAAD	DFS	Quartile	II,III,IV	0.579	0.349	.005	33	view →
HNSC	DFS	Median	IV	0.611	0.474	.003	33	view →
GBM	DFS	Quartile	All	0.159	0.320	.002	30	view →
BLCA	DFS	Quartile	IV	0.123	0.382	.004	29	view →
ESCA	OS	Median	II,III,IV	0.669	0.447	.006	25	view →
THCA	DFS	Tertile	All	0.914	0.784	.004	22	view →
LUSC	OS	Tertile	All	0.736	0.611	.008	20	view →
THYM	OS	Median	All	1.000	0.699	<.001	16	view →
READ	OS	Tertile	II,III,IV	0.866	0.985	.015	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

FGFBP2–KIRC (OS)

Open the KIRC breakdown →