FCN3

Across TCGA patient cohorts, FCN3 mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCN3-associated genes across cancer lineages are BMS1P13, OR6C68, and SNORD116-23. Each is linked with FCN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCN3-to-partner and partner-to-FCN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMS1P13 grouped by FCN3-low versus FCN3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCN3→partner) and Y-score (partner→FCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BMS1P13 →	+0.127	+4.646	<.001	.004	3	2
SKCM	OR6C68 →	+0.018	+4.039	<.001	.009	3	2
SKCM	SNORD116-23 →	+0.280	+3.186	<.001	.009	3	2
HNSC	IFNA10 →	+0.057	+6.608	<.001	.001	3	1
HNSC	RNU6-525P →	+0.489	+5.303	<.001	.006	3	1
HNSC	RNU4-56P →	+0.405	+7.948	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

BMS1P13 by FCN3 expression — COAD

Explore this box plot interactively →