RNA, U6 small nuclear 525, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-525P profile across patient tissues and cancer cell-line models. RNU6-525P expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, RNU6-525P is differentially expressed in 1, with the highest sampling consensus in LUSC. Additionally, RNU6-525P RNA expression shows 5,045 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight KICH, LUSC, and COAD as cancer lineages where RNU6-525P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-525P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-525P survival associations across molecular data types. RNU6-525P RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-525P RNA expression–survival associations across cancer types. High RNU6-525P expression shows unfavorable associations in KICH, KIRP, THCA, PAAD, UVM and BLCA. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for RNU6-525P RNA expression.
This table summarizes RNU6-525P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-525P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-525P shows lower tumor expression in LUSC. The LUSC box plot shows higher RNU6-525P RNA expression in normal versus tumor tissue (log2 FC = −0.137, t-test p = .013).
This table shows molecular features associated with RNU6-525P in patient tissues and cancer cell lines. In patient samples, RNU6-525P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
