FBN2

Across TCGA patient cohorts, FBN2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,206 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBN2-associated genes across cancer lineages are NEDD9, SAMD9L, and SPOCK1. Each is linked with FBN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FBN2-to-partner and partner-to-FBN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBN2 versus NEDD9 in OV, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBN2→partner) and Y-score (partner→FBN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NEDD9 →	+1.208	+1.374	.001	<.001	3	4
UCEC	SAMD9L →	-0.823	-0.832	<.001	.002	3	4
BRCA	SPOCK1 →	+1.090	+0.576	<.001	<.001	3	4
LSCC	TBL1X →	+0.966	+1.407	<.001	<.001	3	3
COAD	CRTAM →	-0.815	-0.615	<.001	<.001	3	3
LSCC	KPNA1 →	+0.593	+1.453	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,206 associations by consensus.

FBN2 vs NEDD9 — OV

Explore this scatter interactively →