FBLL1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FBLL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBLL1-associated genes across cancer lineages are PRR30, TSSK1B, and MTRNR2L6. Each is linked with FBLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBLL1-to-partner and partner-to-FBLL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLL1→partner) and Y-score (partner→FBLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaPRR30 →+0.019+5.269<.001<.00131
BLOOD_LeukemiaTSSK1B →+0.014+4.874<.001.00231
BLOOD_LeukemiaMTRNR2L6 →+0.101+5.269<.001<.00131
LARGE_INTESTINESLC35G3 →+0.006+4.467.007.00431
LARGE_INTESTINEOR14I1 →+0.022+4.415<.001.00731
LARGE_INTESTINECCL23 →+0.403+4.930<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration