Q-omics provides the consensus-scored OR14I1 profile across patient tissues and cancer cell-line models. OR14I1 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, OR14I1 is differentially expressed in 4, with the highest sampling consensus in KICH. Additionally, OR14I1 RNA expression shows 6,873 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, KICH, and STAD as cancer lineages where OR14I1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR14I1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR14I1 survival associations across molecular data types. OR14I1 RNA expression shows survival associations in the most cancer types (16), followed by mutation status (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR14I1 RNA expression–survival associations across cancer types. High OR14I1 expression shows unfavorable associations in ACC, THYM, UCEC, CESC and LUAD, but favorable associations in KIRC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for OR14I1 RNA expression.
This table summarizes OR14I1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for OR14I1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR14I1 shows lower tumor expression in KICH, PRAD and COAD and higher tumor expression in KIRC. The KICH box plot shows higher OR14I1 RNA expression in normal versus tumor tissue (log2 FC = −0.176, t-test p < 0.001).
This table shows molecular features associated with OR14I1 in patient tissues and cancer cell lines. In patient samples, OR14I1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, OR14I1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_SCLC, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and OVARY.
