Across TCGA patient cohorts, OR14I1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR14I1-associated genes across cancer lineages are PCNA, VHL, and CD49b. Each is linked with OR14I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14I1-to-partner and partner-to-OR14I1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14I1→partner) and Y-score (partner→OR14I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.257	+2.700	.008	.006	3	2
UCEC	VHL →	-1.079	-3.584	<.001	.002	3	2
UCEC	CD49b →	-0.318	-3.156	.013	.018	3	2
UCEC	EGFR_pY1068 →	-0.280	-2.000	.013	.032	3	1
UCEC	A-Raf_pS299 →	-0.140	-3.000	.009	.036	3	1
UCEC	Paxillin →	+0.279	+3.179	.016	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

OR14I1 survival (RNA) · tumor vs normal (RNA) · all OR14I1 data types