family with sequence similarity 90 member A27, pseudogeneGenealiases: []
Q-omics provides the consensus-scored FAM90A27P profile across patient tissues and cancer cell-line models. FAM90A27P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, FAM90A27P is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, FAM90A27P RNA expression shows 8,215 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight BLCA, THCA, and THYM as cancer lineages where FAM90A27P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FAM90A27P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FAM90A27P survival associations across molecular data types. FAM90A27P RNA expression shows survival associations in the most cancer types (12), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FAM90A27P RNA expression–survival associations across cancer types. High FAM90A27P expression shows unfavorable associations in BLCA, ESCA, CESC, CHOL, SKCM and LIHC. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify BLCA as the clearest survival context for FAM90A27P RNA expression.
This table summarizes FAM90A27P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for FAM90A27P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FAM90A27P shows higher tumor expression in THCA. The THCA box plot shows higher FAM90A27P RNA expression in tumor versus normal tissue (log2 FC = +0.018, t-test p = .043).
This table shows molecular features associated with FAM90A27P in patient tissues and cancer cell lines. In patient samples, FAM90A27P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.