FAM78A

Across TCGA cell cohorts, FAM78A mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM78A-associated genes across cancer lineages are CPXCR1, OR10V1, and AQP12A. Each is linked with FAM78A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM78A-to-partner and partner-to-FAM78A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPXCR1 grouped by FAM78A-low versus FAM78A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM78A→partner) and Y-score (partner→FAM78A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CPXCR1 →	+0.087	+4.234	<.001	<.001	3	1
BLOOD_Leukemia	OR10V1 →	+0.020	+4.247	<.001	.004	3	1
BLOOD_Leukemia	AQP12A →	+0.119	+4.099	<.001	<.001	3	1
BLOOD_Leukemia	OR1J2 →	+0.063	+4.254	<.001	<.001	3	1
BLOOD_Leukemia	KHDC3L →	+0.162	+3.096	<.001	.005	3	1
BLOOD_Leukemia	OR1J4 →	+0.123	+2.948	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CPXCR1 by FAM78A expression — BLOOD_Leukemia

Explore this box plot interactively →