olfactory receptor family 1 subfamily J member 4Genealiases: HSHTPCRX01 · HTPCRX01 · OR9-21
Q-omics provides the consensus-scored OR1J4 profile across patient tissues and cancer cell-line models. OR1J4 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, OR1J4 is differentially expressed in 8, with the highest sampling consensus in HNSC. Additionally, OR1J4 RNA expression shows 8,250 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KICH, HNSC, and THYM as cancer lineages where OR1J4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR1J4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR1J4 survival associations across molecular data types. OR1J4 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR1J4 RNA expression–survival associations across cancer types. High OR1J4 expression shows unfavorable associations in KICH, PAAD, LGG, LUSC, GBM and MESO. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for OR1J4 RNA expression.
This table summarizes OR1J4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for OR1J4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR1J4 shows higher tumor expression in HNSC, COAD, BLCA, LUSC, KIRC and LIHC. The HNSC box plot shows higher OR1J4 RNA expression in tumor versus normal tissue (log2 FC = +0.176, t-test p < 0.001).
This table shows molecular features associated with OR1J4 in patient tissues and cancer cell lines. In patient samples, OR1J4 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, OR1J4 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_SCLC, while CRISPR and shRNA rows add functional-dependency signals in CNS and BREAST.
