FAM76A

Across TCGA patient cohorts, FAM76A protein abundance is significantly associated with the RNA expression of many other genes, with 8,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM76A-associated genes across cancer lineages are CENPF, KNTC1, and SNRNP40. Each is linked with FAM76A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM76A-to-partner and partner-to-FAM76A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM76A versus CENPF in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM76A→partner) and Y-score (partner→FAM76A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CENPF →	+1.262	+0.314	<.001	<.001	3	5
HNSC	KNTC1 →	+0.742	+0.217	.002	.001	3	5
HNSC	SNRNP40 →	+1.098	+0.274	.003	.001	3	5
HNSC	CDC7 →	+0.767	+0.183	.001	.007	3	5
BRCA	VRK1 →	+0.698	+0.327	<.001	<.001	3	4
LSCC	YY1 →	+0.327	+0.234	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,216 associations by consensus.

FAM76A vs CENPF — BRCA

Explore this scatter interactively →