FAM76A

Across TCGA cell cohorts, FAM76A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,582 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM76A-associated GO terms across cancer lineages are RISC complex assembly, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with FAM76A in more than 12 cancer types. Because this analysis shows association rather than direction, both FAM76A-to-partner and partner-to-FAM76A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by FAM76A-low versus FAM76A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM76A→partner) and Y-score (partner→FAM76A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RISC complex assembly →	+0.108	+0.708	<.001	<.001	3	12
KIDNEY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.137	+0.635	.001	.004	2	13
KIDNEY	Symbiont-mediated disruption of host anatomical structure →	+0.137	+0.635	.001	.004	2	13
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.126	+0.711	<.001	<.001	3	11
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.126	+0.711	<.001	<.001	3	11
LARGE_INTESTINE	Endosomal transport →	+0.047	+0.659	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,582 associations by consensus.

RISC complex assembly by FAM76A expression — LARGE_INTESTINE

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