FAM71E2

Across TCGA patient cohorts, FAM71E2 mutation is significantly associated with the RNA expression of many other genes, with 2,049 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71E2-associated genes across cancer lineages are RNU6-994P, PRAMEF1, and OR10J5. Each is linked with FAM71E2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM71E2-to-partner and partner-to-FAM71E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-994P grouped by FAM71E2-low versus FAM71E2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71E2→partner) and Y-score (partner→FAM71E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-994P →	+0.217	+7.471	<.001	.008	3	3
SCLC	PRAMEF1 →	+0.136	+4.847	<.001	.009	3	2
SCLC	OR10J5 →	+0.098	+4.847	<.001	.009	3	2
COAD	PLA2G12AP1 →	+0.401	+3.301	.005	.007	3	2
UCEC	CORT →	+0.368	+1.562	<.001	.002	3	2
COAD	LINC02446 →	+1.200	+3.335	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,049 associations by consensus.

RNU6-994P by FAM71E2 expression — BRCA

Explore this box plot interactively →