FAM71E2

Across TCGA cell cohorts, FAM71E2 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FAM71E2-associated genes across cancer lineages are C10orf53, GUCA2B, and XAGE5. Each is linked with FAM71E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71E2-to-partner and partner-to-FAM71E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by FAM71E2-low versus FAM71E2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71E2→partner) and Y-score (partner→FAM71E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C10orf53 →	+0.012	+5.954	<.001	<.001	3	1
CNS	GUCA2B →	+0.057	+4.981	<.001	.008	3	1
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
LARGE_INTESTINE	CFAP47 →	+0.273	+2.716	<.001	.009	3	1
LARGE_INTESTINE	ACER1 →	+0.110	+3.408	<.001	<.001	3	1
LARGE_INTESTINE	CTAG1A →	+0.104	+3.285	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

C10orf53 by FAM71E2 expression — SOFT_TISSUE

Explore this box plot interactively →