FAM47E-STBD1

Across TCGA patient cohorts, FAM47E-STBD1 mutation is significantly associated with the RNA expression of many other genes, with 2,452 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM47E-STBD1-associated genes across cancer lineages are FGF21, RN7SL689P, and IKBKE. Each is linked with FAM47E-STBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47E-STBD1-to-partner and partner-to-FAM47E-STBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF21 grouped by FAM47E-STBD1-low versus FAM47E-STBD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47E-STBD1→partner) and Y-score (partner→FAM47E-STBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FGF21 →	+0.352	+1.858	.001	.008	3	2
UCEC	RN7SL689P →	+0.558	+2.169	.001	.003	3	1
UCEC	IKBKE →	-0.624	-1.991	<.001	.009	3	1
UCEC	SUZ12P1 →	+0.475	+2.684	.001	<.001	3	1
UCEC	TIMM23 →	+0.287	+2.592	.008	.006	3	1
UCEC	MIR4768 →	-0.931	-2.676	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,452 associations by consensus.

FGF21 by FAM47E-STBD1 expression — UCEC

Explore this box plot interactively →