FAM47E-STBD1

Across TCGA pan-cancer cohorts, FAM47E-STBD1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of FAM47E-STBD1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where FAM47E-STBD1 RNA is repressed in tumor relative to normal tissue. In most cancer types FAM47E-STBD1 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and LUSC are the cancer types where FAM47E-STBD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM47E-STBD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	−0.167	<.001	11	view →
KICH	Male	All	−0.202	<.001	10	view →
LUSC	All	II,III,IV	−0.166	<.001	9	view →
HNSC	Male	All	−0.086	<.001	8	view →
BRCA	All	III,IV	−0.408	<.001	6	view →
THCA	Male	All	−0.141	.003	6	view →
CHOL	All	All	+0.146	.009	2	view →
LIHC	All	All	+0.041	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

FAM47E-STBD1–LUAD

Open the LUAD breakdown →