FAM47E-STBD1

Across TCGA pan-cancer cohorts, FAM47E-STBD1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FAM47E-STBD1 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FAM47E-STBD1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM47E-STBD1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and ACC show a favorable association.

KIRC, ACC, and BLCA are the cancer types where FAM47E-STBD1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.712	0.551	<.001	133	view →
ACC	OS	Median	All	1.000	0.771	<.001	47	view →
BLCA	OS	Median	IV	0.324	0.574	<.001	37	view →
LUSC	OS	Median	All	0.312	0.468	<.001	35	view →
COAD	DFS	Tertile	II,III,IV	0.649	0.820	.007	27	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	18	view →
KIRP	DFS	Median	All	0.978	0.788	.005	18	view →
SCLC	OS	Quartile	III,IV	0.117	0.569	.008	15	view →
PAAD	DFS	Quartile	All	0.408	0.206	.006	14	view →
CESC	DFS	Quartile	All	0.612	0.770	.007	10	view →
READ	DFS	Tertile	IV	0.325	0.741	.024	9	view →
UCEC	DFS	Median	II,III,IV	0.665	0.788	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FAM47E-STBD1–KIRC (DFS)

Open the KIRC breakdown →