FAM186B

Across TCGA patient cohorts, FAM186B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM186B-associated proteins across cancer lineages are HNRNPU, SRRT, and ZFR. Each is linked with FAM186B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM186B-to-partner and partner-to-FAM186B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM186B versus HNRNPU in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM186B→partner) and Y-score (partner→FAM186B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HNRNPU →	+0.282	+0.522	<.001	<.001	3	7
LSCC	SRRT →	+0.236	+0.495	<.001	<.001	3	6
GBM	ZFR →	+0.217	+0.317	<.001	<.001	3	6
LSCC	ADNP →	+0.306	+0.367	<.001	<.001	3	6
LSCC	GTF3C4 →	+0.380	+0.410	<.001	<.001	3	6
HNSC	NONO →	+0.194	+0.541	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,933 associations by consensus.

FAM186B vs HNRNPU — GBM

Explore this scatter interactively →