FAM168B

Across TCGA patient cohorts, FAM168B mutation is significantly associated with the RNA expression of many other genes, with 2,378 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM168B-associated genes across cancer lineages are TRIM64EP, OR7E16P, and SFPQP1. Each is linked with FAM168B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM168B-to-partner and partner-to-FAM168B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM64EP grouped by FAM168B-low versus FAM168B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM168B→partner) and Y-score (partner→FAM168B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRIM64EP →	+0.042	+4.384	<.001	.008	3	3
CESC	OR7E16P →	+0.028	+4.559	<.001	.006	3	2
CESC	SFPQP1 →	+0.019	+4.757	<.001	.004	3	2
CESC	CBX3P6 →	+0.066	+4.559	<.001	.006	3	2
UCEC	RNU6-1228P →	+0.120	+3.464	.008	.002	3	2
UCEC	RPS27P27 →	+0.277	+1.806	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,378 associations by consensus.

TRIM64EP by FAM168B expression — CESC

Explore this box plot interactively →