FAM167A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM167A mutation is significantly associated with the RNA expression of many other genes, with 3,018 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM167A-associated genes across cancer lineages are RNA5SP418, MIR6780B, and RN7SL804P. Each is linked with FAM167A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM167A-to-partner and partner-to-FAM167A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP418 grouped by FAM167A-low versus FAM167A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM167A→partner) and Y-score (partner→FAM167A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP418 →+0.526+1.863<.001.00233
UCECMIR6780B →+0.269+2.375<.001<.00132
READRN7SL804P →+0.271+5.421<.001.00532
BRCADEFB131A →+0.099+4.571<.001.00532
SARCSNORD114-17 →+0.651+5.477<.001.00432
SARCSNORD96B →+0.471+5.345<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,018 associations by consensus.

RNA5SP418 by FAM167A expression — UCEC

Box plot of RNA5SP418 in FAM167A-low vs FAM167A-high samples in UCEC.

Explore this box plot interactively →

Exploration